Ulcerative colitis hub

Common Symptoms of UC

Last Updated Nov 11, 2025

Ulcerative colitis (UC) often starts in the rectum, then can extend up the colon. Inflammation in this area explains hallmark symptoms like rectal bleeding, bowel urgency, tenesmus, and frequent stools. Symptoms range from mild to severe and can come and go. Knowing the common patterns, and the warning signs of severe disease, helps people act quickly and avoid complications. (mayoclinic.org)

Key takeaways

  • UC commonly causes bright red rectal bleeding, often with mucus. (niddk.nih.gov)

  • Urgency and tenesmus come from rectal inflammation, which is present in most people with UC. (crohnscolitisfoundation.org)

  • Frequent, loose stools occur because inflamed colon lining absorbs less water. (crohnscolitisfoundation.org)

  • Severe disease is suggested by six or more bloody stools daily plus fever, fast heart rate, anemia, or high inflammation markers. (academic.oup.com)

  • Sudden heavy bleeding, severe belly pain, dehydration, or abdominal swelling need urgent medical care. (journals.lww.com)

Why UC causes these symptoms

In UC, inflammation starts in the rectum and spreads in a continuous pattern along the colon. The rectum is a storage area for stool, so when it is inflamed, signals to empty become strong and frequent. Damage to the inner lining leads to bleeding, and reduced water reabsorption causes diarrhea. (crohnscolitisfoundation.org)

The core symptoms

Rectal bleeding

Rectal bleeding is common in active UC. Blood is usually bright red and may be seen on the stool, in the toilet, or on toilet paper. Ongoing bleeding can cause iron deficiency and fatigue. Any new or heavy bleeding should be evaluated to confirm it is from UC and not another cause, such as hemorrhoids. (niddk.nih.gov)

Urgency

Bowel urgency is a sudden, hard‑to‑delay need to pass stool. It can be very distressing and is closely linked to rectal inflammation. Severe urgency often tracks with higher disease activity, and it can lead to leakage in some cases. (crohnscolitisfoundation.org)

Tenesmus

Tenesmus is the feeling of needing to pass stool even when the rectum is empty, or the passage of very small amounts with a sense of incomplete emptying. It reflects rectal inflammation and often occurs together with urgency and rectal pain. (niddk.nih.gov)

Stool frequency and diarrhea

People with active UC often have frequent trips to the bathroom, sometimes at night. Stools are usually loose or watery, and mucus may be present. Frequency rises as more of the colon is involved. The inflamed colon does not absorb water well, which adds to diarrhea. (niddk.nih.gov)

Other common symptoms

Crampy abdominal pain, fatigue, low appetite, weight loss, and low‑grade fever are more likely when inflammation extends beyond the rectum or is more severe. Some individuals notice nausea. These general symptoms often improve as gut inflammation is brought under control. (niddk.nih.gov)

How symptom patterns match disease extent

  • Proctitis (rectum only) often presents with bleeding, urgency, tenesmus, and normal blood tests.

  • Left‑sided colitis adds left‑sided cramps and more frequent bloody diarrhea.

  • Extensive colitis (pancolitis) increases stool frequency and the chance of systemic symptoms like fatigue and weight loss. (mayoclinic.org)

Warning signs of severe disease

Acute severe UC is defined by six or more bloody stools per day plus at least one marker of systemic toxicity, such as fever above 37.8°C (100°F), heart rate above 90 beats per minute, anemia, or elevated inflammatory markers like C‑reactive protein. This pattern usually requires hospital care. (academic.oup.com)

Urgent medical attention is also warranted for any of the following:

  • Continuous or heavy rectal bleeding, dizziness, or fainting. (niddk.nih.gov)

  • Severe or worsening abdominal pain, belly swelling, or inability to pass gas or stool, which can signal complications. (journals.lww.com)

  • Signs of dehydration, such as very dry mouth, dark urine, or inability to keep fluids or medicines down. (niddk.nih.gov)

  • Persistent fever or chills with frequent bloody stools. (journals.lww.com)

Tracking symptoms between visits

Keeping a brief daily log helps teams gauge control and adjust therapy. Useful items include number of stools, how many were bloody, presence of urgency or tenesmus, night‑time stools, and abdominal pain. Many clinics pair these reports with stool calprotectin, blood tests, and occasional endoscopy to confirm remission. (journals.lww.com)

What else can mimic UC symptoms

Hemorrhoids, anal fissures, infections, microscopic colitis, and irritable bowel syndrome can also cause bleeding, urgency, or altered bowel habits. When symptoms change, stool tests and a clinical review help separate a UC flare from other problems. (mayoclinic.org)

Where this fits in the UC hub

Symptoms guide when to escalate care and when to check for healing. For definitions of disease extent, see “How Far Does UC Go (Montreal E1–E3).” For hospital‑level care, see “Acute Severe Ulcerative Colitis (ASUC).” Current treatment strategies that target both symptoms and inflammation are covered in the treatment and medication sections. (journals.lww.com)