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Which IBD medications are usually covered by your insurer?

Select an insurer, medication, and condition to see typical commercial coverage, prior authorization, and step therapy requirements, all based on publicly available formulary policies.

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Covered, PA + step therapy

Yes, with hurdles: Aetna typically requires prior auth and step therapy for Omvoh

Aetna plans generally cover Omvoh (mirikizumab) for ulcerative colitis only after trying a preferred alternative first. Your GI's office can request an exception if step therapy isn't clinically appropriate for you.

Policy as of Jul 2026 ↗
Prior authorization

Required

Prescriber submits clinical documentation; decision times vary by plan, urgency, and how complete the submission is.

Step therapy

Fail-first required

Typically must try Entyvio (vedolizumab); Skyrizi (risankizumab); Pyzchiva or Stelara (ustekinumab); Tremfya (guselkumab); one infliximab biosimilar (Avsola, Inflectra, or Renflexis) first, unless contraindicated.

Typical placement

Positioned behind lower-cost alternatives

medical-benefit policy CPB 1048; not a pharmacy cost-share tier

Line of business:
Commercial
Reauthorization:
Continuation requires documented benefit; CPB 1048 does not state a universal 12-month duration
PA criteria:
Moderate-to-severe active ulcerative colitis; prescribed by or in consultation with a gastroenterologist; precertification required under CPB 1048. Continuation requires objective or symptomatic improvement.
Exception path:
Documented inadequate response (generally after an adequate one-month trial), intolerance, or contraindication to all listed alternatives / medical-necessity exception
Scope:
Aetna commercial medical-benefit CPB 1048 for IV induction; SC maintenance and pharmacy formulary rules are separate.
Read the full guide: Does Aetna cover Omvoh for ulcerative colitis? →Individual plans may differ from the public policy documents cited here. Always confirm with your insurer.

The access landscape for ulcerative colitis

How restrictive each major insurer's standard commercial formulary is, per medication. Select any cell to see the details above.

  • Prior auth
  • PA + step therapy
  • Brand excluded / off formulary
  • Varies by local plan
Aetna
Anthem
Blue Cross Blue Shield
Cigna
Kaiser Permanente
UnitedHealthcare
Entyviovedolizumab
Humiraadalimumab
Omvohmirikizumab
Rinvoqupadacitinib
Skyrizirisankizumab
Stelaraustekinumab
Tremfyaguselkumab

Standard commercial policies; last reviewed Jul 2026. Coverage depends on your exact plan, employer group, state, and whether the drug is infused (medical benefit) or self-injected (pharmacy benefit). Blue Cross Blue Shield coverage is set by independent local Blue companies, and Kaiser Permanente details reflect Kaiser Northwest policy documents. This tool summarizes publicly available policies and is for informational purposes only. Your individual plan may differ from the public documents cited here. It is not medical or insurance advice. Your selections are not saved or sent to a server; they live only in your browser and this page's web address, so you can bookmark or share a result.

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