Research directory
Below are clinical trials currently recruiting participants in the United States.
125 studies
Recently updated first
NCT06538649
This study compares rosuvastatin with placebo after stricture surgery in adults with stricturing Crohn’s disease.
Crohn Disease · Crohn's Ileocolitis
1 recruiting site
Updated Feb 27, 2026
NCT04224558
A single-group study of autologous stem cell transplantation in people ages 13–28 with severe Crohn's disease that has resisted treatment.
Crohn Disease
1 recruiting site
Updated Feb 20, 2026
NCT06647615
A pilot study of daily virtual reality for adults with quiescent Crohn’s disease and weekly abdominal pain.
Abdominal Pain (AP) · Crohn's Disease
1 recruiting site
Updated Feb 17, 2026
NCT06029972
A Phase 2 study comparing oral tilpisertib fosmecarbil doses with placebo in adults with moderately to severely active ulcerative colitis.
Ulcerative Colitis
109 recruiting sites
Updated Feb 11, 2026
NCT07273188
A study of Ga68-FAPI-46 PET/CT imaging in adults with small bowel Crohn's disease, with or without strictures.
Crohn's Disease · Inflamatory Bowel Disease · Intestinal Fibrosis · Intestinal Strictures Related to Crohn´s Disease
1 recruiting site
Updated Feb 9, 2026
NCT07258771
A randomized study compares upadacitinib plus corticosteroids with corticosteroids alone in adults with acute severe ulcerative colitis.
Ulcerative Colitis Acute
1 recruiting site
Updated Feb 2, 2026
NCT05332639
A web-based personalized Crohn’s risk tool is being compared with standard education in unaffected relatives of people with inflammatory bowel disease.
Crohn Colitis · Crohn Disease · Crohn's Duodenitis · Crohn's Esophagitis · Crohn's Gastritis · Crohn's Ileocolitis · Crohn's Jejunitis · Inflammatory Bowel Diseases
1 recruiting site
Updated Jan 30, 2026
NCT05849012
A pilot study compares low sulfur and usual diets in adults with quiescent Crohn’s disease and persistent abdominal pain or diarrhea.
Crohn's Disease in Remission
1 recruiting site
Updated Jan 15, 2026
NCT06257706
A study comparing two vedolizumab treatment-target strategies in adults with moderately to severely active Crohn's disease.
Crohn Disease · Disease Crohn · Moderately to Severely Active Crohn's Disease
60 recruiting sites
Updated Jan 15, 2026
NCT05987852
A randomized sham-controlled study of hyperbaric oxygen therapy in adults hospitalized with moderate-to-severe ulcerative colitis flares.
Ulcerative Colitis
12 recruiting sites
Updated Jan 8, 2026
NCT07219537
A pilot study of an unsedated tethered capsule imaging device in healthy adults and adults with specified gastrointestinal conditions.
Crohn Disease · Healthy · Inflammatory Bowel Diseases · Lynch Syndrome
1 recruiting site
Updated Dec 16, 2025
NCT00692939
A single-group study of high-dose therapy and autologous stem cell transplant in people ages 10–60 with severe Crohn’s disease.
Crohn's Disease
2 recruiting sites
Updated Dec 15, 2025
NCT01962415
A phase 2 study of reduced-intensity conditioning before donor stem cell transplantation in people with eligible noncancer disorders.
Congenital Bone Marrow Failure Syndromes · Hereditary Anemias · Inflammatory Conditions · Inherited Metabolic Disorders (IMD) · Juvenile Rheumatoid Arthritis (JRA) · Primary Immunodeficiency (PID) · Systemic Juvenile Idiopathic Arthritis (sJIA)
1 recruiting site
Updated Dec 15, 2025
NCT06721962
A phase 1/2 study of TRX103 in adults with moderate-to-severe Crohn’s disease that has not responded to multiple advanced therapies.
Crohns Disease
13 recruiting sites
Updated Dec 10, 2025
NCT07115862
A 16-week study of daily pomegranate juice in adults with mild-to-moderate ulcerative colitis.
Ulcerative Colitis (Disorder)
2 recruiting sites
Updated Dec 9, 2025
NCT07195123
A randomized study of whether the SMART-IBD smartphone app improves medication adherence and self-management among adolescents with inflammatory bowel disease.
Crohn Disease (CD) · IBD · IBD - Inflammatory Bowel Disease · IBD (Inflammatory Bowel Disease) · Indeterminate Colitis · Inflammatory Bowel Disease (IBD) · Ulcerative Colitis (UC)
1 recruiting site
Updated Nov 21, 2025
NCT07168499
This randomized study tests diet and stress-management support alongside advanced therapy in adults with active inflammatory bowel disease.
IBD (Inflammatory Bowel Disease)
1 recruiting site
Updated Nov 6, 2025
NCT07033208
This study tests whether a swallowed wireless capsule can collect gastrointestinal temperature data from healthy adults.
Crohn Disease · Healthy · Inflammatory Bowel Diseases
1 recruiting site
Updated Oct 22, 2025
NCT06420492
A Phase 2 study of BRS201 in adults with acute severe ulcerative colitis that has not responded to treatment.
Ulcerative Colitis · Ulcerative Colitis Chronic Moderate · Ulcerative Colitis Chronic Severe
2 recruiting sites
Updated Oct 20, 2025
NCT04314375
A Phase 4 study of budesonide or placebo in children ages 5–17 with active mild-to-moderate ulcerative colitis.
Ulcerative Colitis
4 recruiting sites
Updated Sep 16, 2025
